Compliment Activation (or Geeky Fun with Words)

This has been a tough week in the world, so I thought you might like a little diversion.

Sometimes I hear interesting words or phrases that pique my curiosity. These three phrases suggested meanings, but when I checked, I discovered the real meanings were very different.

Compliment activation – What I hope will happen after I get my hair cut or if I’m showing off a new pair of shoes.

When I first heard this term at a medical conference in a previous life, I was delighted. After all, I’m a writer and love expressive language. But if you spell this the scientific way —“complement activation,” you get the real meaning:

The complement system includes 20+ protein molecules that circulate in the blood. When the body senses a pathogen (the cooties that cause disease), the complement system is activated and a sequence of events occurs to fight infection. So either kind of complement activation can be good for you.

Antisense – Sounds like a good description for current events. Also might describe what the chipmunks in my yard are saying.

“Antisense” just covers so many situations. Turns out, it also has a scientific meaning: Having a sequence of nucleotides complementary to (and hence capable of binding to) a coding sequence, which may be either that of the strand of a DNA double helix that undergoes transcription, or that of a messenger RNA molecule (Dictionary.com).

Whaaaat?

After more research, I learned that the concept of antisense evolved into a therapy for genetic disorders. When a particular gene is responsible for a disease, a strand of nucleic acid can be bound to the messenger RNA of that gene and effectively switch off the disease-causing gene.

Regional expression – OK, I think I got this. A regional expression is like “pop” in the Midwest or “soda” on the East coast. Or maybe the way I say, “crick” for “creek” – an Ohio thing. Unless we’re talking about genetics.

Every gene contains a particular set of instructions that code for a specific protein. Gene expression is the process that enables DNA instructions to be converted into something useful, such as a protein. Where a gene lies in the genome (its region or neighborhood) influences the regulation of gene expression. In other words, gene behavior is influenced by where it hangs out. Hmm. Just like people.

It can’t hurt to know a bit more about genetics, but I like my definitions better!

Advertisements

Celebrating Retirement

Last week I celebrated one year of retirement. “Celebrated” is a key word. While I was happy to retire last August, I felt a little undercurrent of worry—I didn’t exactly have a plan. For many people, not having a plan sounds like what retirement is all about. But to me, making such a major and irreversible move called for a blueprint. As in what I am I going to do for the rest of my life? Which suddenly seemed more finite.

Retirement is an Identity Change

Retirement is a major identity shift akin to starting a career, marrying a spouse, or becoming a parent. You see yourself differently. A wise friend advised that it might take up to a year to figure out retirement, and it has.

Who Am I Without My Profession?

Americans often identify with our professions. I have worked since I was 16, and I babysat before that, so paid work has been part of my life since I was 11. I went to some effort (getting a graduate degree, moving across the country three times) to launch my career—first as a teacher and then as a copywriter. In 1979, when I started teaching college full-time, the working world wasn’t welcoming to women, and I had to fight to belong. By the time I started copywriting five years later, I had toughened up and the workplace was less openly antagonistic. My early experiences shaped me, and having a career became an integral part of who I am.

My other roles—wife, mother, sister, and friend—have remained constant in retirement. But last August I wondered, “What does it mean to let go of the career I worked so hard to have? What happens to all the experience and skills I’ve gained?” Today, the answer is that I’m still a writer—an essayist and blogger, and I volunteer as a marketing communications copywriter.

Me in retirement--just kidding--it's Rose Totino

Me in retirement–just kidding!

That’s how I see myself, but early on when I mentioned my new status, I learned that the word “retiree” conjures up someone who’s out-of-touch and lives for coupons. Now when I meet people, I simply describe the work I do.Ellen in Hawaii

 

 

 

 

 

 

 

People Openly Wonder, “What do you do all day?”

It’s a legitimate question. A year ago, I too wondered how to create a life that is fulfilling and fun. What exactly was I going to do with my time? The answer is more of everything I did before. I sleep half-an-hour longer. Most days, I walk for an hour because now exercising doesn’t have to be a trade-off (i.e., either I exercise or I have fun).

Housework, cooking, and grocery shopping still exist in retirement. I’m determined not to become obsessive about any of that, but now I might take an extra five minutes to dry the pots and pans after I wash them instead of letting them air dry as I did before. Why not? I have time.

Camping in WI

Camping in WI

Today, I read, write, travel, socialize, and volunteer more. Probably the main difference is that now I have more time to explore or learn new things in classes at the University of Minnesota, the Loft, or community education.

I wasn’t planning to retire last August at 61; I expected to work two-and-a-half more years. However, when a stroke of luck gave me the opportunity to leave early, I did. I am very grateful to be retired now. Eventually old age will find me. But for now I’m enjoying the gift of retirement. I want to use my time well.